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Von Frey纖毛機械刺激針（Von Frey hairs test Von Frey Filaments， Semmes-Weinstein monofilament 含20根Von Frey尼龍纖維絲，它可提供0.008g-300g的刺激力可對多種動物進行定量的痛覺測試，主要用于von Frey hairs test評估皮膚的機械痛閾或觸覺閾測量。

Von Frey hairs纖毛機械刺激針的粗細及伸出長度決定提供刺激力的大小。實驗時，根據(jù)實際情況選定粗細當?shù)玫腣on Frey hairs纖毛機械刺激針，調(diào)節(jié)適當Von Frey hairs纖毛機械刺激針的伸出長度，垂直地刺激皮膚，可通過調(diào)節(jié)伸長、更換Von Frey hairs纖毛機械刺激針調(diào)整刺激力大小，直到Von Frey hairs纖毛機械刺激針彎曲。當嚙齒類動物得爪受到一個機械刺激，它們會縮回反射。該觸覺測試可應用于大、小鼠的足底。

另外，可選配鑿孔工作臺，其網(wǎng)篩孔是利用激光切沖而成的方形孔，尺寸為5×5mm2 ，孔間距約為1mm，這對受試動物而言是一個舒適的環(huán)境，也便于操作人員觀察動物的足底區(qū)域。該鑿孔臺經(jīng)涂層處理，便于清潔且不易被腐蝕。

主要技術(shù)參數(shù)：

Von Frey hairs纖毛機械刺激針尼龍絲：no°20，校準偏差小于5%

Von Frey hairs test 刺激力：0.008-300g

Touch Test

The Semmes-Weinstein monofilaments provide an approximate logarithmic scale of actual force， and a linear scale of perceived intensity. They have a long history of effective use in clinical settings， and can be used to diagnose pathologies of hyper- or hypo-aesthesia. Subsets within the set of 20 probes distinguish pathologies on different parts of the body (foot， hand， lip， cheek，etc.).

Semmes-Weinstein Von Frey Aesthesiometer for touch assessment

Features

Set of 20 monofilaments based on the Semmes-Weinstein monofilament set

Features retractable filaments to protect the filament

Allows the researcher to carry a few in a pocket

The Semmes-Weinstein monofilaments provide an approximate logarithmic scale of actual force， and a linear scale of perceived intensity. They have a long history of effective use in clinical settings， and can be used to diagnose pathologies of hyper- or hypo-aesthesia. Subsets within the set of 20 probes distinguish pathologies on different parts of the body (foot， hand， lip， cheek，etc.).

Operating Principle When the tip of a fiber of given length and diameter is pressed against the skin at right angles， the force of application increases as long as the researcher continues to advance the probe， until the fiber bends. After the fiber bends， continued advance creates more bend， but not more force of application. This makes it possible for the researcher using a hand-held probe to apply a reproducible force， within a wide tolerance， to the skin surface.

Pre-Clinical Use Rodents exhibit a paw withdrawal reflex when the paw is unexpectedly touched. The Touch Test? Sensory Evaluator can be used on the Plantar surfaces of the foot of a rat or mouse. The animal indicates sensation by pulling back its paw. Individual filaments available.

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